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Cleft lip is a birth defect that involves an opening or separation in the upper lip. The opening can vary in size, from a small notch to a complete separation that extends up into the nose. Cleft lip can occur on one side of the lip (unilateral) or both sides (bilateral). Cleft lip is a common birth defect, affecting about 1 in every 700 babies born in the United States. It is more common in boys than in girls. The exact cause of cleft lip is unknown, but it is thought to be a combination of genetic and environmental factors.
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